#共同一作;*通讯作者;更新至2025.03
1. Wang YX*, Dumas O, Varraso R, Sun Y,Rich-Edwards JW, Manson JE, Mukamal KJ, Zhang Y, Camargo CA, Messerlian C. Occupational exposure to disinfectants and risk of incident cardiovascular disease among US nurses: the Nurses' Health Study II. Environ Health Perspect, 2025 Mar 31. doi: 10.1289/EHP14945
2. Li YP, Liu C, Mustieles V, Zhang Y, Messerlian C, Gaskins AJ, Chen HG, Chen YJ, Xu QT, Zhao XY, Wang H, Meng TQ, Pan A, Mei SR*, Wang YX*. Organophosphate Esters, Sperm Mitochondrial DNA Copy Number, and Semen Quality: A Longitudinal Study with Repeated Measurements. Environ Sci Technol. 2025 Feb 25; 59(7):3388-3400
3. Wang YX*, Farland LV, Gaskins AJ, Wang S, Terry KL, Rexrode KM, Rich-Edwards JW, Tamimi R, Chavarro JE, Missmer SA. Endometriosis and uterine fibroids and risk of premature mortality: prospective cohort study. BMJ, 2024, 387:e078797
4. Li G, Xu S, Pan SS, Shao HL, Gaskins AJ, Zhang Y, Sun Y, Mustieles V, Pan A, Liu C*, Jing LM*, Wang YX*. Hypertension and semen quality among 1381 young men: A cohort study with repeated measurements. Innovation Med, 2024, 2(4): 100099
5. Tian M*, Li H, Wu S, Xi H, Wang YX*, Lu YY, Wei L, Huang Q*. Exposure to haloacetic acid disinfection by-products and male steroid hormones: An epidemiological and in vitro study. J Hazard Mater, 2024, 468:133796
6. Li G, Xu S, Messerlian C, Zhang Y, Chen YJ, Sun Y, Mustieles V, Wang Y, Pan A, Liu C*, Wang YX*. Blood trihalomethane and urinary haloacetic acid concentrations in relation to hypertension: An observational study among 1162 healthy men. J Hazard Mater, 2024, 477:135411
7. Li Y, Zheng Z, Luo D, Liu C, Yang S, Chen Y, Hu Q, Lu W, Wang YX*, Mei S*. Reproductive hormones, organophosphate esters and semen quality: Exploring associations and mediation effects among men from an infertility clinic. Environ Res, 2024, 240(Pt 1):117458
8. Lu ZH, Liu C, Chen YJ, Chen YJ, Lei XN, Cai LJ, Zhou HX, Chang H, Zhu M, Wang YX*, Zhang J*. Gestational Exposure to PM2.5 and Specific Constituents, Meconium Metabolites, and Neonatal Neurobehavioral Development: A Cohort Study. Environ Sci Technol, 2024, 58(23):9980-9990
9. Chen YJ, Messerlian C, Lu Q, Mustieles V, Zhang Y, Sun Y, Wang L, Lu WQ, Liu C*, Wang YX*. Urinary haloacetic acid concentrations in relation to sex and thyroid hormones among reproductive-aged men. Environ Int, 2024, 189:108785
10. Wang YX*, Yang Sun, Missmer SA, Rexrode KM, Wang L, Roberts Al, Chavarro JE, Rich-Edwards JW. Association of Childhood Physical and Sexual Abuse with Risk of Premature Mortality in Women: a Prospective Cohort Study. BMJ, 2023, 381:e073613
11. Wang YX*, Mitsunami M, Manson JE, Gaskins AJ, Rich-Edwards JW, Wang L, Zhang C, Chavarro JE. Association of Gestational Diabetes Mellitus with Subsequent Long-term Risk of Mortality: A Large Prospective Cohort Study. JAMA Intern Med, 2023,183(11):1204-1213
12. Sun Y, Wang YX*, Mustieles V, Shan Z, Zhang Y, Messerlian C. Blood trihalomethane concentrations and allergic sensitization: A nationwide cross-sectional study. Sci Total Environ, 2023, 871:162100
13. Wang YX*, Raphalle Varraso, Orianne Dumas, Jennifer J. Stuart, Andrea Florio, Liang Wang, Janet W. Rich-Edwards, Carlos A. Camargo, Jr, Jorge Chavarro. Hypertensive disorders of pregnancy and risk of asthma and chronic obstructive pulmonary disease: a prospective cohort study. Lancet Reg Health Am, 2023, 23:100540
14. Chen HG, Sun B, Lin F, Chen YJ, Xiong CL, Meng TQ, Duan P, Messerlian C, Hu Z, Pan A, Ye W*, Wang YX*. Sperm mitochondrial DNA copy number mediates the association between seminal plasma selenium concentrations and semen quality among healthy men. Ecotoxicol Environ Saf, 2023, 251:114532
15. Sun Y, Wang YX*, Qian D, Mustieles V, Zhang Y, Messerlian C. Blood Trihalomethane Concentrations and Osteoarthritis among U.S. Population Aged over 50 Years. Environ Sci Technol, 2023, 57(43):16166-16175
16. Liu C, Chen YJ, Sun B, Chen HG, Mustieles V, Messerlian C, Sun Y, Meng TQ, Lu WQ, Pan XF, Xiong CL*, Hou J*, Wang YX*. Blood trihalomethane concentrations in relation to sperm mitochondrial DNA copy number and telomere length among 958 healthy men. Environ Res, 2023, 216(Pt 4):114737
17. Wang YX*, Stuart JJ, Rich-Edwards JW, Missmer SA, Rexrode KM, Farland5 LV, Mukamal KJ, Nelson SM, Solomon CG, Fraser A, Chavarro JE. Menstrual cycle regularity and length across the reproductive lifespan and risk of cardiovascular disease: a prospective cohort study. JAMA Netw Open, 2023, 5(10):e2238513
18. Li Y, Luo D, Zhao X, Wang H, Zheng Z, Liu J, Liu C, Wang H, Chen Y, Shang Y, Lu W, Mei S*, Wang YX*. Urinary concentrations of organophosphate esters in relation to semen quality: A cross-sectional study, Sci Total Environ, 2023, 865:161202
19. Liu N, Chen hg, Yu Lia Y, Zhang G, Zhang J, Qu G, He B, Meng TQ, Xiong CL, Pan A, Yin Y, Liang Y, Shi J, Wang YX*, Hu L*, Jianga GB. Exogenous Metals Atlas in Spermatozoa at Single-Cell Resolution in Relation to Human Semen Quality. Environ Sci Technol, 2023, 57(19):7358-7369
20. Sun Y, Wang YX*, Liu C, Mustieles V, Pan XF, Zhang Y, Messerlian C. Exposure to Trihalomethanes and Bone Mineral Density in US Adolescents: A Cross-Sectional Study (NHANES). Environ Sci Technol, 2023, 57(51):21616-21626
21. Lu ZH, Sun B, Wang YX*, Wu YR, Chen YJ, Sun SZ, Liang SJ, Xu S, Chang H, Chen HG, Zhang J*. Ozone exposure associates with sperm quality indicators: Sperm telomere length as a potential mediating factor, J Hazard Mater, 2023, 459:132292
22. Sun B, Chen HG, Duan P, Tu ZZ, Chen YJ, Meng TQ, Xiong CL, Wang YX*, Pan A*. Association of handgrip strength with semen characteristics: a study with repeated measurements among healthy Chinese men. Asian J Androl, 2022,24(6):594-600
23. Tian M*, Wu S, Wang YX*, Liu L, Zhang J, Shen H, Lu Y, Bao H, Huang Q*. Associations of environmental phthalate exposure with male steroid hormone synthesis and metabolism: An integrated epidemiology and toxicology study. J Hazard Mater, 2022, 436:129213
24. Xu S, Wu Y, Chen Y, Lu W, Wang YX*, Gao B, Zhang J*. Environmental metal exposure, seminal plasma metabolome and semen quality: Evidence from Chinese reproductive-aged men. Sci Total Environ, 2022, 838(Pt 2):155860
25. Wang YX*, Arvizu M, Rich-Edwards JW, Manson JM, Wang L, Missmer SA, Chavarro JE. Breastfeeding duration and subsequent risk of mortality among US women: results from two prospective cohort studies. eClinicalMedicine, 2022, 54:101693
26. Wang YX*, Li Y, Rich-Edwards JW, Florio AA, Shan Z, Wang S, Manson JE, Mukamal KJ, Rimm EB, Chavarro JE. Associations of birth weight and later life lifestyle factors with risk of cardiovascular disease in the USA: A prospective cohort study. eClinicalMedicine, 2022, 51: 101570
27. Sun B, Hou J*, Ye YX, Chen HG, Duan P, Chen YJ, Xiong CL, Wang YX*, Pan A*. Sperm mitochondrial DNA copy number in relation to semen quality: A cross-sectional study of 1164 potential sperm donors. BJOG, 2022, 129(13):2098-2106
28. Wang YX*, Ding M, Li Y, Wang L, Rich-Edwards JW, Florio A, Manson JE, Chavarro JE. Birth weight and risk of total and cause-specific mortality among US men and women: results from three prospective cohort studies. Lancet Reg Health Am, 2022,15: 100344
29. Ye YX, Chen HG, Sun B, Chen YJ, Duan P, Meng TQ, Xiong CL, Wang YX*, Pan A*. Associations between depression, oxidative stress, and semen quality among 1,000 healthy men screened as potential sperm donors. Fertil Steril, 2022,117(1):86-94
30. Sun Y, Wang YX*, Mustieles V, Zhang Y, Pan XF, Messerlian C. Association of blood trihalomethane concentrations with lung function in U.S. adolescents: a nationally representative cross-sectional study. Eur Respir J, 2022, 60(1):2200753
31. Chen YJ, Liu C, Tu ZZ, Lu Q, Messerlian C, Mustieles V, Sun Y, Lu WQ, Pan XF, Mao C*, Wang YX*. Associations of Urinary Trichloroacetic Acid Concentrations with Spermatozoa Apoptosis and DNA Damage in a Chinese Population. Environ Sci Technol, 2022, 56(10):6491-6499
32. Sun Y, Xia PF, Korevaar T, Mustieles V, Zhang Y, Pan XF, Wang YX*, Messerlian C. Relationship between Blood Trihalomethane Concentrations and Serum Thyroid Function Measures in U.S. Adults. Environ Sci Technol, 2021, 55(20):14087-14094
33. Sun Y, Chen C, Mustieles V, Wang L, Zhang Y, Wang YX*, Messerlian C. Association of Blood Trihalomethane Concentrations with Risk of All-cause and Cause-specific Mortality in U.S. Adults: A Prospective Cohort Study. Environ Sci Technol, 2021, 55(13):9043-9051
34. Chen HG, Lu Q, Tu ZZ, Chen YJ, Sun B, Hou J, Xiong CL, Wang YX*, Meng TQ*, Pan A*. Identifying windows of susceptibility to essential elements for semen quality among 1428 healthy men screened as potential sperm donors. Environ Int, 2021155:106586
35. Wang YX, Wang SW, Mitsunam M, Pan A, Manson JE, Rich-Edwards JW, Wang L, Zhang CL, Chavarro JE. Pre-pregnancy menstrual cycle regularity and length and the risk of gestational diabetes mellitus: prospective cohort study. Diabetologia, 2021, 64(11):2415-2424
36. Wang YX, Mínguez-Alarcón L, Gaskins A, Arvizu M, Missmer S, Rich-Edwards JW, Manson J, Pan A, Chavarro JE. Association of spontaneous abortion with all cause and cause specific premature mortality: prospective cohort study. BMJ, 2021, 372:n530
37. Wang YX*, Farland l, Wang S, Gaskins A, Wang L, Rich-Edwards J, Tamimi R, Missmer S, Chavarro J. Association of infertility with premature mortality among US women: Prospective cohort study. Lancet Reg Health Am, 2021,100122
38. Liu C, Messerlian C, Chen YJ, Mustieles V, Huang LL, Sun Y, Deng YL, Cheng YH, Liu J, Liu AM, Lu WQ*, Wang YX*. Trimester-specific associations of maternal exposure to disinfection by-products, oxidative stress, and neonatal neurobehavioral development. Environ Int, 2021,157:106838
39. Wang YX, Arvizu M, Rich-Edwards JW, Wang L, Rosner B, Stuart JJ, Rexrode KM, Chavarro JE. Hypertensive disorders of pregnancy and subsequent risk of premature mortality: a prospective cohort study. 2021, JACC, 2021, 77 (10) 1302–1312
40. Liu C, Sun Y, Mustieles V, Chen YJ, Huang LL, Deng YL, Wang YX*, Lu WQ*, Messerlian C. Prenatal Exposure to Disinfection Byproducts and Intrauterine Growth in a Chinese Cohort. Environ Sci Technol. 2021 Dec 7;55(23):16011-16022
41. Sun Y, Xia PF, Xie J, Mustieles V, Zhang Y, Wang YX*, Messerlian C. Association of blood trihalomethane concentrations with asthma in U.S. adolescents: nationally representative cross-sectional study. 2021, Eur Respir J, 2021 Oct 8;2101440.
42. Wang YX, Mínguez-Alarcón L, Wang L, Ding M, Missmer S, Rich-Edwards JW, Manson J, Chavarro JE. Spontaneous abortion and risk of cardiovascular disease: the Nurses’ Health Study II. Eur Heart J, 2021,43(3):190-199
43. Wang LM, Luo D, Li X, Hu LQ, Chen JX, Tu ZZ, Sun B, Chen HG, Liu L, Yu M, Li YP, Pan A, Messerlian C, Mei SR*, Wang YX*. Temporal variability of organophosphate flame retardant metabolites in spot, first morning, and 24-hour urine samples among healthy adults. Environ Res, 2020,110373
44. Chen YJ, Duan P, Meng TQ, Chen HG, Chavarro JE, Xiong CL, Pan A*, Wang YX*, Lu WQ*, Messerlian C. Associations of Blood Trihalomethanes with Semen Quality among 1199 Healthy Chinese Men Screened as Potential Sperm Donors. Environ Int, 2020,134:105335
45. Liu C, Wang YX*, Chen YJ, Sun Y, Huang LL, Cheng YH, Liu EN, Lu WQ*, Messerlian C. Blood and urinary biomarkers of prenatal exposure to disinfection byproducts and oxidative stress: A repeated measurement analysis. Environ Int, 2020, 137:105518
46. Tian M*, Wang YX*, Wang X, Wang H, Liu L, Zhang J, Nan B, Shen H, Huang Q*. Environmental doses of arsenic exposure are associated with increased reproductive-age male urinary hormone excretion and in vitro Leydig cell steroidogenesis. J Hazard Mater, 2020, 408:124904
47. Wang YX, Arvizu M, Rich-Edwards JW, Stuart JJ, Manson JE, Missmer SA, Pan A, Chavarro JE. Menstrual cycle regularity and length across the reproductive lifespan and risk of premature mortality: prospective cohort study. BMJ, 2020, 371:m3464
48. Chen HG, Sun B, Chen YJ, Chavarro JE, Hu SH, Xiong CL, Pan A*, Meng TQ*, Wang YX*, Messerlian C. Sleep duration and quality in relation to semen quality in healthy men screened as potential sperm donors. Environ Int. 2020 Feb:135:105368
49. Sun Y, Wang YX*, Wang Q, Liu C, Chen YJ, Lu WQ*, and Messerlian C. Trimester-Specific Blood Trihalomethane and Urinary Haloacetic Acid Concentrations and Adverse Birth Outcomes: Identifying Windows of Vulnerability during Pregnancy. Environ Health Perspect, 2020,128(10):107001
50. Wang YX, Shan ZL, Arvizu M, Pan A, Manson JE, Missmer SA, Sun Q, Chavarro JE. Associations of menstrual cycle characteristics across the reproductive life span and lifestyle factors with risk of type 2 diabetes: a cohort study. JAMA Netw Open, 2020, 3(12):e2027928
51. Wang YX#, Wu Y#, Chen HG, Duan P, Wang L, Shen HQ, Lu WQ, Sun B, Wang Q, Zhang B, Chavarro JE, Zhang J, Pan A. Seminal plasma metabolome in relation to semen quality and urinary phthalate metabolites among Chinese adult men. Environ Int, 2019, 129:354-363.
52. Chen HG, Lu WQ, Wang YX*, Pan A*. Reproducibility of essential elements chromium, manganese, iron, zinc and selenium in spot samples, first-morning voids and 24-h collections among healthy adult men. Br J Nutr, 2019, 122(3):343-351
53. Wang YX, Pan A, Feng W, Liu C, Huang LL, Ai SH, Zeng Q, Lu WQ. Variability and exposure classification of urinary levels of non-essential metals aluminum, antimony, barium, thallium, tungsten and uranium in healthy adult men. J Expo Sci Environ Epidemiol, 2019, 29(3):424-434
54. Wang YX, Liu C, Chen YJ, Duan P, Wang Q, Chen C, Sun Y, Huang LL, Wang L, Chen C, Li J, Ai SH, Huang Z, Sun L, Wan ZZ, Pan A, Meng TQ, Lu WQ. Profiles, variability and predictors of concentrations of blood trihalomethanes and urinary haloacetic acids along pregnancy among 1760 Chinese women. Environ Res, 2019, 172:665-674
55. Chen YJ, Liu C, Huang LL, Ai SH, Sun Li, Huang Z, Li J, Lei HS, Li J, Liu YA, Wang X, Liu XY, Cheng YH, Wang YX*, Pan A*, Lu WQ*. First-trimester blood concentrations of drinking water trihalomethanes and neonatal neurobehavioral development in a Chinese birth cohort. J Hazard Mater, 2019, 362:451-457
56. Wang YX#, Liu C#, Shen Y#, Wang Q, Pan A, Yang P, Chen YJ, Deng YL, Lu Q, Cheng LM, Miao XP, Xu SQ, Lu WQ, Zeng Q. Urinary levels of bisphenol A, F and S and markers of oxidative stress among healthy adult men: Variability and association analysis. Environ Int, 2019, 123:301-309
57. Sun B, Messerlian C, Sun ZH, Duan P, Chen HG, Chen YJ, Wang P, Wang L, Meng TQ, Wang Q, Arvizu M, Chavarro JE, Wang YX*, Xiong CL*, Pan A*. Physical Activity and Sedentary Time in Relation to Semen Quality in Healthy Chinese Men Screened as Potential Sperm Donors. Hum Reprod, 2019, 34(12):2330-2339
58. Liu C, Messerlian C, Chen C, Meng TQ, Duan P, Hu SH, Liu Y, Chen HG, Sheng LT, Sun B, Wang Q, Wang L, Chavarro J, Arvizu M, Xiong CL, Pan A*, Lu WQ*, Wang YX*. Mediation of the Relationship between Phthalate Exposure and Semen Quality by Oxidative Stress among 1034 Reproductive-aged Chinese Men. Environ Res, 2019,108778
59. Wang YX, Zhou B, Chen YJ, Liu C, Huang LL, Liao JQ, Hu XJ, Lu WQ, Zeng Q, Pan A. Thyroid function, phthalate exposure and semen quality: Exploring associations and mediation effects in reproductive-aged men. Environ Int, 2018, 116:278-285
60. Wang YX, Liu C, Chen YJ, Chen HG, Yang P, Wang P, Huang LL, Ai SH, Duan P, Pan A, Zeng Q, Lu WQ. Predictors and correlations of phthalate metabolite concentrations in urine and seminal plasma among reproductive-aged men. Environ Res, 2018,161:336-344
61. Wan ZZ, Chen HG, Lu WQ, Wang YX*, Pan A*. Metal/metalloid levels in urine and seminal plasma in relation to computer-aided sperm analysis motion parameters. Chemosphere, 2018, 214:791-800
62. Huang LL, Zhou B, Ai SH, Yang P, Chen YJ, Liu C, Deng YL, Lu Q, Miao XP, Lu WQ, Wang YX*, Zeng Q*. Prenatal phthalate exposure, birth outcomes and DNA methylation of Alu and LINE-1 repetitive elements: A pilot study in China. Chemosphere, 2018, 206:759-765.
63. Wang YX, Chen HG,c Li XD, Chen YJ, Liu C, Feng W, Zeng Q, Wang P, Pan A, Lu WQ. Concentrations of vanadium in urine and seminal plasma in relation to semen quality parameters, spermatozoa DNA damage and serum hormone levels. Sci Total Environ, 2018, 645:441-448
64. Hu D#, Wang YX#, Chen WJ, Zhang Y, Li HH, Xiong L, Zhu HP, Chen HY, Peng SX, Wan ZH, Zhang Y, Du YK. Associations of phthalates exposure with attention deficits hyperactivity disorder: A case-control study among Chinese children. Environ Pollut. 2017, 229:375-385
65. Wang YX, Wang P, Feng W, Liu C, Yang P, Chen YJ, Sun L, Sun Y, Yue J, Gu LJ, Zeng Q, Lu WQ. Relationships between seminal plasma metals/metalloids and semen quality, sperm apoptosis and DNA integrity. Environ Pollut, 2017, 224:224-234
66. Wang YX, Feng W, Zeng Q, Sun Y, Wang P, You L, Yang P, Huang Z, Yu SL, Lu WQ*. Variability of Metal Levels in Spot, First Morning, and 24-Hour Urine Samples over a 3-Month Period in Healthy Adult Chinese Men. Environ Health Perspect. 2016,124(4):468-76
67. Wang YX, Sun Y#, Huang Z, Wang P, Feng W, Li J, Yang P, Wang M, Sun L, Chen YJ, Liu C, Yue J, Gu LJ, Zeng Q, Lu WQ. Associations of urinary metal levels with serum hormones, spermatozoa apoptosis and sperm DNA damage in a Chinese population. Environ Int, 2016,177-188
68. Wang YX, Zeng Q, Sun Y, Yang P, Wang P, Li J, Huang Z, You L, Huang YH, Wang C, Li YF, Lu WQ. Semen phthalate metabolites, semen quality parameters and serum reproductive hormones: A cross-sectional study in China. Environ Pollut, 2016, 211:173-82
69. Wang YX, Sun Y, Feng W, Wang P, Yang P, Li J, Huang Z, Chen YJ, Liu C, Sun L, Yue J, Gu LJ, Zeng Q, Lu WQ. Association of urinary metal levels with human semen quality: A cross-sectional study in China. Environ Int, 2016, 51-9
70. Wang YX, Zeng Q, Sun Y, You L, Wang P, Li M, Yang P, Li J, Huang Z, Wang C, Li S, Dan Y, Li YF, Lu WQ. Phthalate exposure in association with serum hormone levels, sperm DNA damage and spermatozoa apoptosis: A cross-sectional study in China. Environ Res,2016,150:557-65
71. Wang YX, You L, Zeng Q, Sun Y, Huang YH, Wang C, Wang P, Cao WC, Yang P, Li YF, Lu WQ. Phthalate exposure and human semen quality: Results from an infertility clinic in China. Environ Res, 2015,142:1-9
72. Wang YX#, Zeng Q#, Wang L, Huang YH, Lu ZW, Wang P, He MJ, Huang X, Lu WQ. Temporal variability in urinary levels of drinking water disinfection byproducts dichloroacetic acid and trichloroacetic acid among men. Environ Res, 2014,135:126-32